Endocrine Abstracts

Background: A rare cause of ectopic Cushing’s Syndrome (ECS) is pulmonary neuroendocrine neoplasm (NEN) with a broad spectrum of clinical behavior. At the time of diagnosis, pulmonary NENs may present as occult tumors or well-defined round-to-oval lesions in close relationship to the bronchus. Herein, we describe a NEN that developed ECS three years later in a patient followed up for a solitary pulmonary nodule (SPN).Case Presentation: A 56-year-old...

Introduction: Wolfram syndrome, is a rare autosomal recessive genetic disorder that is characterized by diabetes mellitus (DM), diabetes insipidus (DI), optic atrophy, and sensorineural deafness as well as various other possible disorders. DM is the first manifestation, and optic atrophy also onsets in the first decade of life. The onsets of DI and sensorineural deafness are in the second decade, urinary tract abnormalities are in the third decade, and neurologic abnormalities...

AimsWe aimed to reveal the impacts of dapagliflozin, a sodium glucose transporter inhibitor (SGLT2i), on the body weight and body composition, cardiovascular risk indexes, and carotis intima-media thickness (CIMT).MethodsBody weights, body compositions measured by means of bioelectrical impedance, and CIMT in the baseline, the 12th, and the 24th week of 42 patients with type-2 diabetes mellitus receiving SGLT...

PurposeThyroid hormones are known to have an essential role in the regulation of energy homeostasis and glucose metabolism. Considering to literature data, variations of thyroid hormones within normal ranges change in obesity and type 2 diabetes mellitus (T2DM) in opposite ways. This study aims to evaluate thyroid hormone levels and fT3/fT4 ratio in different glucose metabolism statuses of euthyroid patients with obesity.Methods</p...

Background: The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis has effects on renal growth and electrolyte regulation. However, data on adverse renal comorbidities such as renal cysts and stones in acromegaly is scarce. The current study aimed to investigate the prevalence of radiologically detectable renal comorbidities and possible related factors in the acromegaly population.Methods: A total of 125 patients with acromegaly (46.4&pm;11.6...

Background: Hypophysitis is a rare group of disease characterized with infla mmation of the pituitary gland. Rarity of the disease obviates development of a treatment strategy. We aimed to present the nationwide data of the demographics, clinical and radiological characteristics, treatment modalities and responses of the patients diagnosed with hypophysitis in a retrospective manner.Methods: The endocrinology clinics all over the country were invited to ...